Association Between the Epidemiological Profile and the Heart Electrical Function of Patients with Chagas Disease

Authors

  • Lineker Fernandes Dias Universidade Federal de Uberlândia – Uberlândia (MG), Brazil. https://orcid.org/0000-0002-6256-7139
  • Stefan Vilges de Oliveira Universidade Federal de Uberlândia – Uberlândia (MG), Brazil.

Keywords:

Epidemiology, Electrocardiography, ambulatory, Trypanosoma cruzi, Medical records

Abstract

Objective: To analyze the association between the epidemiological profile and cardiac electrical function in patients with Chagas disease. Method: This is a descriptive, cross-sectional study, based on the analysis of medical records from a teaching hospital in Minas Gerais. The association of the epidemiological characteristics of the individuals included in the study with the results of their ECGs was analyzed. Results: 70 medical records were evaluated. Most of the sample was elderly (81.42), with a predominance of males (47.14%), and white ethnicity (50%). Left bundle branch blocks (18.57%) and left and right bundle branch blocks (11%), left ventricular overload (71.43%) and secondary changes in ventricular repolarization (21.43%) were the predominant electrophysiological changes. When checking the association between the epidemiological profile and cardiac electrical function, the only significant association was between the variables ethnicity and atrioventricular blocks (AVB). Conclusion: Among the residents of Minas Gerais with CD, elderly white men likely tend to develop AVB.

 

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References

Chagas C. Nova tripanozomiaze humana: estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. gen., n. sp., ajente etiolojico de nova entidade morbida do homem. Mem. Inst. Oswaldo Cruz. 1909; 1(2): 159-218. doi: 10.1590/S0074-02761909000200008.

Control of Chagas disease: second report of the WHO expert committee [internet]. Geneva; World Health Organization; 2002. [citado 24 ago 2021]. Disponível em: <https://apps.who.int/iris/handle/10665/42443>.

Dias JCP. Epidemiology of Chagas Disease in Brazil. Chagas Disease Vectors. Boca Raton: CRC PRESS INC. 1987; 2: 59-75. doi: 10.1590/S0074-02762004000300004.

Chagas disease (American trypanosomiasis) Fact sheet N°340. [internet]. Geneva; World Health Organization; 2015. [citado 24 ago 2021]. Disponível em: <http://www.who.int/mediacentre/factsheets/fs340/en/>.

Bern C, Kjos S, Yabsley MJ, Montgomery SP. Trypanosoma cruzi and Chagas disease in the United States. Clin. Microbiol. Rev. 2011; 24(4): 655-681. doi: 10.1128/CMR.00005-11.

Hotez PJ, Fujiwara RT. Brazil's neglected tropical diseases: an overview and a report card. Microbes. Infect. 2014; 16(8): 601-606. doi: 10.1016/j.micinf.2014.07.006.

Martins-Melo FR et al. Prevalence of Chagas disease in Brazil: a systematic review and meta-analysis. Acta Trop. 2014; 130: 167-174. doi: 10.1016/j.actatropica.2013.10.002.

Martins-Melo FR, Alencar CH, Ramos AN, Heukelbach J. Epidemiology of mortality related to Chagas' disease in Brazil, 1999-2007. PLOS Negl. Trop. Dis. 2012; 6(2): 1999-2007. doi: 10.1371/journal.pntd.0001508.

Biolo A, Ribeiro AL, Clausell N. Chagas cardiomyopathy - where do we stand after a hundred years?. Prof. Cardiovasc. Dis. 2010; 52(4), 300-316. doi: 10.1016/j.pcad.2009.11.008.

Ribeiro AL, Nunes MP, Teixeira MM, Rocha MO. Diagnosis and management of Chagas disease and cardiomyopathy. Nat Rev Cardiol. 2012; 9(10): 576–589. doi: 10.1038/nrcardio.2012.109.

Chagas C, Villela E. Forma cardíaca da trypanosomiase americana. Mem. Inst. Oswaldo Cruz. 1922; 14(1): 5-61. doi: 10.1590/S0074-02761922000100001.

Brito BODF, Ribeiro ALP. Electrocardiogram in Chagas disease. Rev. Soc. Bras. Med. Trop. 2018; 51: 570-577. doi: 10.1590/0037-8682-0379-2018.

Cardoso RN et al. Chagas cardiomyopathy is associated with higher incidence of stroke: a meta-analysis of observational studies. J Card Fail. 2014; 20(12): 931-938. doi: 10.1016/j.cardfail.2014.09.003.

Oliveira-Filho J. et al. Chagas disease is an independent risk factor for stroke: baseline characteristics of a Chagas Disease cohort. Stroke. 2005; 36(9): 2015-2017. doi: 10.1161/01.STR.0000177866.13451.e4.

Espinosa R et al. Life expectancy analysis in patients with Chagas' disease: prognosis after one decade (1973–1983). Int. J. Cardiol. 1985; 8(1): 45-56. doi: 10.1016/0167-5273(85)90262-1.

Maguire JH et al. Cardiac morbidity and mortality due to Chagas’ disease: prospective electrocardiographic study of a Brazilian community. Circulation. 1987; 75(6): 1140-1145. doi: 10.1161/01.CIR.75.6.1140.

Hamer SA, Curtis-Robles R, Hamer GL. Contributions of citizen scientists to arthropod vector data in the age of digital epidemiology. Curr. Opin. Insect Sci. 2018; 28: 98-104. doi: 10.1016/j.cois.2018.05.005.

Brasil. Instituto Brasileiro de Geografia e Estatística (IBGE) [internet]. Brasília; 2010. [acesso em 24 out 2021]. Disponível em: <https://www.ibge.gov.br/cidades-e-estados/mg/uberlandia.html>.

Brasil. Empresa Brasileira de Serviços Hospitalares [internet]. Brasília; 2020. [citado 24 ago 2021]. Disponível em: < https://www.gov.br/ebserh/pt-br/hospitais-universitarios/regiao-sudeste/hc-ufu/acesso-a-informacao/institucional/sobre>.

Oliveira F. Ser negro no Brasil: alcances e limites. Estud. Av. 2004; 18: 57-60. doi: 10.1590/S0103-40142004000100006.

Siqueira AL, Tibúrcio, JD. Estatística na área da saúde: conceitos, metodologia, aplicações e prática computacional. Belo Horizonte (MG). COOPMED. 2011.

Brasil. Conselho Nacional de Saúde. Resolução nº. 510 de 07 de abril de 2016. Dispõe sobre as normas aplicáveis a pesquisas em Ciências Humanas e Sociais. Diário Oficial da União 24 de maio 2016; Seção 1.

Alencar MMF et al. Epidemiologia da Doença de Chagas aguda no Brasil de 2007 a 2018. Res., Soc. Dev. 2020; 9(10): e8449109120. doi: 10.34119/bjhrv3n5-007.

Dias JC et al. 2nd Brazilian Consensus on Chagas Disease, 2015. Ver. Soc. Bras. Med. Trop. 2016; 49: 3-60. doi: 10.1590/0037-8682-0505-2016.

Bastos SQDA, Gomes BS, Bonioli RS. Uma avaliação para média complexidade do plano diretor de regionalização da saúde de Minas Gerais (PDR/MG). RDE-Revista de Desenvolvimento Econômico. 2019; 2(43): 111-135. doi: 10.36810/rde.v2i43.5995.

Moraes DN. et al. Value of the electrocardiographic (P Wave, T Wave, QRS) axis as a predictor of mortality in 14 years in a population with a high prevalence of Chagas disease from the Bambui cohort study of aging. Am. J. Cardiol. 2018; 121(3), 364-369. doi: 10.1016/j.amjcard.2017.10.020.

Rojas LZ et al. Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis. PLoS Negl Trop Dis. 2018; 12(6):e0006567. doi: 10.1371/journal.pntd.0006567.

Friedman A et al. Electrocardiogram abnormalities in older individuals by race and ethnicity. J Electrocardiol. 2020; 63: 91-93. doi: 10.1016/j.jelectrocard.2020.09.014.

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Published

2022-12-09

How to Cite

Dias, L. F., & Oliveira, S. V. de. (2022). Association Between the Epidemiological Profile and the Heart Electrical Function of Patients with Chagas Disease. JOURNAL OF CARDIAC ARRHYTHMIAS, 35(1). Retrieved from https://jca.emnuvens.com.br/jca/article/view/3471

Issue

Section

Clinical Arrythmia